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Juha M. Lahnakoski, D.Sc. (Tech.) Neuroimaging IT / Postdoctoral Researcher
Visiting researcher:
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Research interests
My current research focuses on systematic study of differences in brain activity patterns as well as bodily and gaze behavior in individuals with difficulties in social cognition and interaction such as individuals with autism, borderline personality disorder or major depressive disorder compared with healthy typically developed individuals. This research takes a transdiagnostic approach with an aim of finding similarities in symptoms and underlying brain correlates contributing to problems in social interactions across diagnostic categories.
In a parallel line of research I study the brain basis of social perception and perspective taking during viewing of naturalistic audiovisual stimulation such as movies. Main focus is on modeling complex stimuli, and developing and applying novel signal analysis methods for fMRI and eye gaze data gathered during viewing of dynamic audiovisual stimuli.
Publications
Submitted/Under revision
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Aksiuto AA, Lahnakoski JM, Kauttonen J, Saarimäki HK, Volynets S, Nummenmaa L, Sams M, Jääskelainen IP. Psychopathic traits predict neural responses to emotional movies in the general population. doi:10.1101/2023.07.31.551268 [preprint]
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Saarimäki H, Nummenmaa L, Volynets S, Santavirta S, Aksiuto A, Sams M, Jääskelainen IP, Lahnakoski JM. Cerebral Topographies of Perceived and Felt Emotions. doi:10.1101/2023.02.08.521183 [preprint]
Peer reviewed journals
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Lahnakoski JM, Bennett E, Nummenmaa L, Steinert U, Sams M, Svärd S. Embodied Emotions in Ancient Neo-Assyrian Texts Revealed by Bodily Mapping of Emotional Semantics. iScience 111365. doi: 10.1016/j.isci.2024.111365 [Open access article] preprint doi:10.31234/osf.io/kyufj [preprint]
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Rinne P, Lahnakoski JM, Saarimäki H, Tavast M, Sams M, Henriksson L (2024). Six types of loves differentially recruit reward and social cognition brain areas. Cereb Cortex 34: bhae331. doi: 10.1093/cercor/bhae331 [Open access article]
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Lahnakoski JM, Nolte T, Solway A, Vilares I, Hula A, Feigenbaum J, Lohrenz T, Fonagy P, Montague PR, Schilbach L (2024) A machine-learning approach for differentiating borderline personality disorder from community participants with brain-wide functional connectivity. J Affect Disord 360: 345-353. doi:10.1016/j.jad.2024.05.125. (prerint doi:10.31219/osf.io/gdqru) [Open access article]
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Haaf R, Brandi M-L, Albantakis L, Lahnakoski JM, Henco L, Schilbach L (2024) Peripheral oxytocin levels are linked to hypothalamic gray matter volume in autistic adults: A cross-sectional secondary data analysis. Sci Rep 14: 1380. doi:10.1038/s41598-023-50770-5 [Article]
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Alho J, Panula J, Lahnakoski J, Rikandi E, Mäntylä T; Lindgren M, Kieseppä T, Suvisaari J, Sams M, Raij TT (2023) Hippocampus-centered network is associated with positive symptom alleviation in first-episode psychosis patients. Biol Psychiatry Cogn Neurosci Neuroimaging. doi:10.1016/j.bpsc.2023.06.002 [Pre-proof]
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Saalasti S, Alho J, Lahnakoski JM, Bacha-Trams M, Glerean E, Jääskeläinen IP, Hasson U, Sams M (2022) Lipreading a naturalistic narrative in a female population: neural characteristics shared with listening and reading. Brain Behav e2869. doi: 10.1002/brb3.2869 bioRxiv doi:10.1101/233676 [Link to published article] [bioRxiv]
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Lahnakoski JM, Eickhoff SB, Dukart J, Schilbach L (2022) Naturalizing psychopathology - towards a quantitative real-world psychiatry. Mol psychiatry 27, 781–783. doi: 10.1038/s41380-021-01322-8 [pdf]
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Brandi M-L, Lahnakoski JM, Kopf-Beck J, Nolte T, Brückl TM, Schilbach L (2021) Imagery of negative interpersonal experiences influence the neural mechanisms of social interaction. Neuropsychologia 160: 107923. doi: 10.1016/j.neuropsychologia.2021.107923 [Link to published article]
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Bolis D, Lahnakoski JM, Seidel D, Tamm J, Schilbach L (2020) Interpersonal similarity of autistic traits predicts friendship quality. Soc Cogn Affect 16:1–10. doi: 10.1093/scan/nsaa147 [Link to published article]
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Henco L, Diaconescu AO, Lahnakoski JM, Brandi M-L, Hörmann S, Hennings J, Hasan A, Papazova I, Strube W, Bolis D, Schilbach L, Mathys C (2020) Aberrant computational mechanisms of social learning and decision-making in schizophrenia and borderline personality disorder. PLoS Comp Biol. doi:10.1371/journal.pcbi.1008162 [Link to published article]
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Lahnakoski JM, Forbes PAG, McCall C, Schilbach L (2020) Unobtrusive tracking of interpersonal orienting and distance predicts the subjective quality of social interactions. R Soc Open Sci 7:191815. doi:10.1098/rsos.191815 [Link to published article]
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Henco L, Brandi ML, Lahnakoski, JM, Diaconescu AO, Mathys C, Schilbach L (2020) Bayesian modelling captures inter-individual differences in social belief computations in the putamen and insula. Cortex. doi:10.1016/j.cortex.2020.02.024 [Article on publisher's site]
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Brandi M-L, Kaifel D, Lahnakoski JM, Schilbach L (2019). A naturalistic paradigm simulating gaze-based social interactions for the investigation of social agency. Behav Res Methods. doi:10.3758/s13428-019-01299-x [pdf]
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Zillekens IC, Brandi M-L, Lahnakoski JM, Koul A, Manera V, Becchio C, Schilbach L. (2019) Increased functional coupling of the left amygdala and medial prefrontal cortex during the perception of communicative point-light stimuli. Soc Cogn Affect Neurosci 14: 97–107. doi:10.1093/scan/nsy105 [Link to published article]
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Karjalainen T, Seppälä K, Glerean E, Karlsson HK, Lahnakoski JM, Nuutila P,Jääskeläinen IP, Hari R, Sams M, Nummenmaa L (2018) Opioidergic regulation of emotional arousal: A combined PET-fMRI study. Cereb Cortex. bhy281. doi:10.1093/cercor/bhy281 [Link to published article]
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Nummenmaa L, Lahnakoski JM, Glerean E (2018) Sharing the social world via intersubject neural synchronization. Curr Opin Psychol 24: 7–14. doi:10.1016/j.copsyc.2018.02.021 [link to published article]
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Smirnov D, Lachat F, Peltola T, Lahnakoski JM, Koistinen O-P, Glerean E, Vehtari A, Hari R, Sams M, Nummenmaa L. (2017) Brain-to-brain hyperclassification reveals action-specific motor mapping of observed actions in humans. PLoS One 12(12): e0189508. doi:10.1371/journal.pone.0189508 [pdf]
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Bacha-Trams M, Glerean E, Dunbar RIM, Lahnakoski JM, Ryyppö E, Sams M, Jääskeläinen IP. (2017) Differential inter-subject correlation of brain activity when kinship is a variable in moral dilemma. Sci Rep 7: 14244. doi: 10.1038/s41598-017-14323-x [pdf] bioRxiv doi:10.1101/112383 [bioRxiv]
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Karjalainen T, Karlsson HK, Lahnakoski JM, Glerean E, Nuutila P, Jääskeläinen IP, Hari R, Sams M, Nummenmaa L. (2017) Dissociable roles of cerebral μ-opioid and type 2 dopamine receptors in vicarious pain: A combined PET-fMRI study. Cereb Cortex 27: 4257–4266. doi:10.1093/cercor/bhx129 [pdf]
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Lahnakoski JM, Jääskeläinen IP, Sams M, Nummenmaa L (2017) Neural mechanisms for integrating consecutive and interleaved natural events. Hum Brain Mapp 38: 3360–3376. doi:10.1002/hbm.23591 [link to published article] [Uncorrected manuscript]
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Glerean E, Pan RK, Salmi J, Kujala R, Lahnakoski JM, Roine U, Nummenmaa L, Leppämäki S, Nieminen-von Wendt T, Tani P, Saramäki J, Sams M, Jääskeläinen IP (2016) Reorganization of functionally connected brain subnetworks in high-functioning autism. Hum Brain Mapp 37: 1066–1079. doi:10.1002/hbm.23084 [pdf]
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Jääskeläinen IP, Halme H-L, Agam Y, Glerean E, Lahnakoski JM, Sams M, Tapani K, Ahveninen J, Manoach D (2016) Neural mechanisms supporting evaluation of others' errors in real-life like conditions. Sci Rep 6: 18714. doi:10.1038/srep18714 [pdf]
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Smirnov D, Glerean E, Lahnakoski JM, Salmi J, Jääskeläinen IP, Sams M, Nummenmaa L (2014) Fronto-parietal network supports context-dependent speech comprehension. Neuropsychologia 63: 293–303. doi:10.1016/j.neuropsychologia.2014.09.007 [pdf]
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Lahnakoski JM, Glerean E, Jääskeläinen IP, Hyönä J, Hari R, Sams M, Nummenmaa L (2014) Synchronous brain activity across individuals underlies shared psychological perspectives. NeuroImage 100: 316–324. doi:10.1016/j.neuroimage.2014.06.022 [pdf]
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Salmi J, Glerean E, Jääskeläinen IP, Lahnakoski JM, Kettunen J, Lampinen J, Tikka P, Sams M (2014) Posterior Parietal Cortex Activity Reflects the Significance of Others' Actions During Natural Viewing. Hum Brain Mapp 35: 4767–4776. doi:10.1002/hbm.22510 [pdf]
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Nummenmaa L, Smirnov D, Lahnakoski JM, Glerean E, Jääskeläinen IP, Sams M, Hari R (2014) Mental Action Simulation Synchronizes Action-Observation Circuits Across Individuals. J Neurosci 34: 748–757. doi:10.1523/jneurosci.0352-13.2014 [pdf]
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Salmi J, Roine U, Glerean E, Lahnakoski J, Nieminen-von Wendt T, Tani P., Leppämäki S, Nummenmaa L, Jääskeläinen IP, Carlson S, Rintahaka P, Sams M (2013) The brains of high functioning autistic individuals do not synchronize with those of others. Neuroimage: Clinical 3: 489–497. doi:10.1016/j.nicl.2013.10.011 [pdf]
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Glerean E, Salmi J, Lahnakoski JM, Jääskeläinen IP, Sams M (2012) Functional Magnetic Resonance Imaging Phase Synchronization as a Measure of Dynamic Functional Connectivity. Brain connect. 2(2): 91–101. doi:10.1089/brain.2011.0068 [pdf]
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Lahnakoski JM, Glerean E, Salmi J, Jääskeläinen IP, Sams M, Hari R and Nummenmaa L (2012) Naturalistic fMRI mapping reveals superior temporal sulcus as the hub for the distributed brain network for social perception. Front Hum Neurosci 6:233. doi:10.3389/fnhum.2012.00233 [pdf]
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Lahnakoski JM, Salmi J, Jääskeläinen IP, Lampinen J, Glerean E, Tikka P, Sams M (2012) Stimulus-Related Independent Component and Voxel-Wise Analysis of Human Brain Activity during Free Viewing of a Feature Film. PLoS ONE 7(4): e35215. doi:10.1371/journal.pone.0035215 [pdf]
Book chapter
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Schilbach L, Lahnakoski JM (2023) Clinical Neuroscience Meets Second-Person Neuropsychiatry, in: Boggio PS, Wingenbach TSH, da Silveira Coêlho ML, Comfort WE, Murrins Marques L, Alves MVC (Ed.), Social and Affective Neuroscience of Everyday Human Interaction. Springer International Publishing, Cham, pp. 177–191. doi: 10.1007/978-3-031-08651-9_11 [Open access]
International meetings
- Lahnakoski J, Albantakis L, Brandi M-L, Henco L, Eickhoff S, Dukart J, Schilbach L. Aberrant social orienting and extrinsic functional connectivity during natural viewing in autism. 2020 Annual meeting of the Organization for Human Brain Mapping, June 23-July 3, Virtual Conference
- Lahnakoski J & Brückl T, Brandi M-L, Kopf-Beck J, Sämann P, Schilbach L. Interpersonal stress increases the reliability of fMRI responses to autobiographical stories - 2018 Annual meeting of the Organization for Human Brain Mapping, June 17-24, 2018, Singapore. [abstract]
- Lahnakoski JM, Forbes P, Schilbach L. Optical body and face orientation tracking as a non-invasive proxy for social gaze during real-life social interactions. Interactive Eye Gaze, February 12-13, London, United Kingdom.
- Lahnakoski J, Nolte T, Solway A, Vilares I, Hula A, Feigenbaum J, Lohrenz T, Fonagy P, Montague PR, Schilbach L - Full-brain network-based classification of borderline personality disorder - Poster at 2017 Annual meeting of the Organization for Human Brain Mapping, June 25-29, 2017, Vancouver, Canada.
- Lahnakoski JM, Glerean E, Jääskeläinen IP, Hyönä J, Hari R, Sams M, Nummenmaa L - Synchronous brain activity across individuals underlies shared mental perspectives - Nanosymposium presentation at Neuroscience 2013, Annual Meeting of the Society for Neuroscience, November 9-13, 2013, San Diego, CA, USA.
- Lahnakoski J, Jääskeläinen IP, Sams M, Nummenmaa L - Brain mechanisms supporting the following of multiple parallel action sequences - Nanosymposium presentation at Neuroscience 2012, Annual Meeting of the Society for Neuroscience, October 13-17, 2012, New Orleans, LA, USA.
- Lahnakoski J, Jääskeläinen IP, Salmi J, Hari R, Sams M, Nummenmaa L - Perspective Taking Modulates Intersubject Synchronization of Brain Activity during Natural Viewing - Poster at 17th Annual Meeting of the Organization for Human Brain Mapping, June 26-30, 2011, Quebec City, Canada. [pdf]
- Lahnakoski J, Salmi J, Jääskeläinen IP, Lampinen J, Glerean E, Tikka P, Sams M - Activity in the human visual and auditory cortex during watching a movie: an fMRI study - Poster at 16th Annual Meeting of the Organization for Human Brain Mapping, June 6-10, 2010, Barcelona, Spain. [pdf]
Dissertation
- Lahnakoski J - Brain Mechanisms Underlying Perception of Naturalistic Social Events. Aalto University publication series DOCTORAL DISSERTATIONS, 183/2014. ISBN: 978-952-60-5958-7 (electronic) 978-952-60-5957-0 (printed) [pdf].
Competitions
- 2016 Predictive Analytics in Mental Health Competition, First place
Academic activities
- 2020 Educational course contributor, Neuroimaging Analysis Methods For Naturalistic Data, 2020 Annual meeting of the Organization for Human Brain Mapping, doi:10.5281/zenodo.3937849
- 2010-2015 Course assistant, Advanced course on human brain functioning, Aalto University School of Science
- 2013 Member of the student council of the Brain&Mind Doctoral Program
Funding
- 2024–2027 Deutsche Forschungsgemeinschaft Co-investigator
- 2015 Finnish Cultural Foundation post-doctoral grant
- 2013 Brain&Mind Doctoral Program
